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At Accredo, we share your goals of managing your therapy for high cholesterol and improving your overall health. Your Accredo team is here to provide the personalized care and support you need to meet your therapy goals. You have come to the right place for convenient online tools and education to help you get started on your medication.

What can we help you with today?

Whether or not you are new to injection therapy, it is important that you follow the instructions included with your medication shipment. You can access training videos from the manufacturer of your medication at the link below. Or you can call your Accredo care team with any questions about your therapy at 1.855.315.6123.

Praluent® Patient Education

Repatha™ Patient Education

Good injection tips:

  • Always wash your hands before injecting your medication
  • Ensure the area where you inject is clean
  • NEVER inject in an area where the skin is has stretch marks, scars, is irritated, sunburned, bruised or swollen
  • To prevent injection soreness – rotate the site of injection each time you give administer your medication
  • If you are on other injectable medications
    • Inject at least 1 inch away from other injection sites
    • Only inject using supplies specific to each medication
    • Never mix medications in a single syringe or re-use needles
  • Check your medication before injecting to ensure all necessary injection supplies are present, your injection is not damaged or expired, and that there are no particles or color changes to your medication
  • Dispose of needles and syringes safely
  • Place all needles and syringes in a hard, plastic container – properly labeled
  • Do not re-cap needles after use
  • Do not overfill sharps container
  • Once ¾ full, secure lid (if using a re-purposed household container – tape shut)
  • NEVER put sharps in your regular trash or recycling
  • Visit http://www.fda.gov/safesharpsdisposal to learn more or to find your community’s proper disposal locations
  • Create a ROUTINE:    Take your injection at the same day and time every week.
    • This helps you build a schedule, and keeps the medication dosing consistent
    • You can use your smart-phone alarm or a calendar to keep track of when doses are taken and when your next dose is due
  • RELAX! You can do this. While an injection may be intimidating, using good technique can make it manageable. Practice makes perfect
  • REWARD yourself…
    • Feel empowered knowing that you are taking control of your heart health by staying consistent with a heart-healthy lifestyle, your Praluent® and other cholesterol medications. 
    • Some people reward themselves by taking their injection before a favorite activity (like a “can’t miss” TV show, a cup of coffee, or a favorite magazine).   
  • If you ever have questions or want more injection tips, here are some helpful RESOURCES:
    • Praluent® - MyPraluent nurses available at 1.844.PRALUENT (1.844.772.5836)
    • Repatha™ - RepathaReady nurses available at 1.844.REPATHA (1.844.737.2842)
    • Or contact your Accredo care team at 1.855.315.6123. Pharmacists are on call 24/7 for urgent clinical needs.
National heart, lung, blood institute

High blood cholesterol affects approximately 71 million Americans[1].  Untreated, high blood cholesterol levels can double your risk for heart disease. High blood cholesterol is influenced by family predisposition and lifestyle choices.  Treating high blood cholesterol decreases risk of heart attacks both in people with prior heart disease or at high risk for heart disease. 

There are different types of cholesterol in the body.   Low density lipoprotein (LDL) is frequently called “bad” cholesterol, because it is associated with increased heart disease risk.  However, high density lipoprotein (HDL) is often called “good cholesterol” because it is associated with a decreased risk of heart disease. Other types of cholesterol particles, such as very low density lipoprotein (vLDL) and triglycerides can also be dangerous if too high. 

Rarely, extremely high LDL cholesterol levels can be caused by genetic mutations affecting the ability to process cholesterol normally. These genetic diseases are called familial hypercholesterolemias.  Over time, high blood cholesterol builds up as plaque in the walls of the arteries supplying blood to the heart.  This causes inflammation and blockage of the blood supply to the heart, brain, and other organs – ultimately leading to increased risk of heart attack, stroke, and vascular disease.  There are no symptoms of high blood cholesterol, but many with high blood cholesterol have other conditions which multiply their risk of heart disease and stroke.

In order for your high blood cholesterol therapy to work properly, you should work with your healthcare provider to start a heart-healthy diet and exercise plan as well as control other risk factors (such as blood pressure, diabetes, diet and exercise choices, and stopping smoking). 

Other resources:

PCSK9 inhibitors are a new class of drugs that target and eliminate proprotein convertase subtilisin kexin 9, a protein found in the liver.  Deactivating this protein allows for more efficient removal of LDL cholesterol (LDL-C), also called “bad cholesterol”, by the liver, dramatically lowering LDL-C levels in the blood.

PCSK9 therapy available at Accredo includes: 

Praluent® is indicated for use in patients 18 and older with heart healthy diet and other cholesterol-lowering drugs called “statins with high LDL-C who either have:

  • Heterozygous familial hypercholesterolemia (an inherited condition that causes high levels of LDL), or
  • One of the following types of pre-existing heart disease:
    • Past history of heart attack
    • Diagnosis of angina (stable or unstable)
    • Past history of stroke or transient ischemic attack
    • Peripheral arterial disease
    • Patient who has undergone a coronary artery bypass graft surgery or stent placement in the heart

If you are not to LDL-C goal on the maximum tolerated dose of your statin therapy or other lipid-lowering drugs, or if you cannot take statins, your doctor may add Praluent® to your cholesterol treatment plan. 

Limits of Use

The effect of Praluent® on heart problems such as heart attacks, stroke, or death is not known.

It is not known if Praluent® is safe and effective in children.

Praluent® is NOT approved for patients with homozygous (double mutation) familial hypercholesterolemia, and has NOT been studied with Kynamro® or Juxtapid®. 

Dose

Take exactly as prescribed.  Praluent® is given as 75mg or 150mg under the skin every other week.  Your doctor should check your cholesterol again within 4-8 weeks to see how you’re responding. 

Potential side effects include:: allergic reactions, injection site reactions, symptoms of common cold, elevations in liver enzymes.  For more information, and a complete list of side effects see the Praluent product information.

Report any side effects to your doctor. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding to see if this medicine is right for you.

Storage and Stability

  • Accredo will ship Praluent® to you in temperature-sensitive packaging,  Once received, un-pack from the shipping cooler and store Praluent® in your refrigerator at 36°F to 46°F (2°C to 8°C)
    • Do NOT use if your dose has been left out at room temperature (>77°F (25°C)) for more than24 hours.
    • Keep in outer carton in order to protect from light.
    • Do NOT freeze.
    • Do NOT expose to extreme heat.
    • Do NOT shake; it could cause your medicine to be less effective.
    • Do NOT use if syringe or pen has been dropped or damaged.

If you miss a dose, take it as soon as you remember but no more than 7 days late. If closer than 7 days to your next injection, just resume dosing on your next regular day.

For more information on injection, visit the medication administration section of this page.

Report any side effects to your doctor. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding to see if this medicine is right for you.

Repatha™ is indicated for use with heart healthy diet and other cholesterol-lowering drugs called "statins" with high LDL-C who either have:

  • Heterozygous (HeFH) or homozygous familial hypercholesterolemia (HoFH) -an inherited condition that causes high levels of LDL, or
  • One of the following types of pre-existing heart disease:
    • Past history of heart attack
    • Diagnosis of angina (stable or unstable)
    • Past history of stroke or transient ischemic attack
    • Peripheral arterial disease
    • Patient who has undergone a coronary artery bypass graft surgery or stent placement in the heart

If you are not to LDL-C goal on the maximum tolerated dose of your statin therapy or other lipid-lowering therapies (including apheresis for FH), or if you cannot take statins, your doctor may add Repatha™ to your cholesterol treatment plan.

Limits of Use

The effect of Repatha™ on heart problems such as heart attacks, stroke, or death is not known.

Homozygous FH patients known to have two LDL-receptor negative alleles (little to no LDL receptor function) did not respond to Repatha™.

It is not known if Repatha™ is safe and effective in children younger than 13 with homozygous FH or in children who have other types of hyperlipidemia.

Dose

Take exactly as prescribed.

For HeFH or primary hyperlipidemia, Repatha™ is given as 140mg under the skin every other week OR 420mg under the skin monthly.

For HoFH, Repatha is given as 420mg under the skin monthly.

Your doctor should check your cholesterol again within 4-8 weeks to see how you’re responding.

Potential side effects include: allergic reactions, injection site reactions, symptoms of common cold,muscle soreness. For more information, and a complete list of side effects see the Repatha™ product information.

Dose

  • Accredo will ship Repatha™ to you in temperature-sensitive packaging, Once received, un-pack from the shipping cooler and store Repatha™ in your refrigerator at 36°F to 46°F (2°C to 8°C).
    OR you may store Repatha™ at room temperature (up to 25°C (77°F)) up to 30 days.
    • Do NOT use if your dose has been left out at room temperature for more than 30 days.
  • ALWAYS Keep in outer carton in order to protect from light.
  • Do NOT freeze.
  • Do NOT expose to extreme heat.
  • Do NOT shake; it could cause your medicine to be less effective.
  • Do NOT use if syringe or pen has been dropped or damaged.

If you miss a dose, take it as soon as you remember but no more than 7 days late. If closer than 7 days to your next injection, just resume dosing on your next regular day.


Staying connected is now easier than ever because we offer several convenient options to receive prescription updates and shipment notifications. You tell your Accredo team how you would like to hear from us and we will contact you when your next delivery is being processed. If you need to modify or cancel your order, please call us at 1.855.315.6123 within three business days of the notification.



Register on Accredo.com

To view your profile and order status online, please visit www.accredo.com and click the ‘Patient Log In’ link.

  • Accredo now offers you online tools to manage your specialty medications from the convenience and privacy of wherever you have internet access!

Check the order status of your specialty shipments

  • Log in and click on “Order Status” to see the status of recently scheduled medication shipments.

All rights in the product names, trade names or logos of all third-party products that appear in this form, whether or not appearing with the trademark symbol, belong exclusively to their respective owners.

 

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